![](https://cdn.statically.io/img/static01.nyt.com/packages/flash/multimedia/ICONS/transparent.png)
Dr. Isabella L. Karle with her husband, Dr. Jerome Karle, in an undated photo.
Naval Research Laboratory; thumbnail, Naval Research Laboratory, undated
Isabella L. Karle
Died on October 3, 2017 at age 95
Dr. Karle’s experiments elucidating the shapes of molecules contributed crucially to her husband’s Nobel Prize in Chemistry. Her husband, Dr. Jerome Karle, was deeply disappointed that she did not share in the prize.
Notable Deaths 2017
Remembering Mary Tyler Moore, Chuck Berry, Jerry Lewis, David Rockefeller, Trisha Brown, Glen Campbell, Dick Gregory, Edith Windsor, Sam Shepard, Tom Petty and many others who died this year.