This category is for cyborgs who have cybernetic prosthetics—replacements for body parts that were damaged or lost to disease, trauma, or condition of birth. The prosthesis may or may not fully replicate the capabilities of a non-modified body part. It is not inclusive of non-disabled beings who elected to modify their bodies.

Examples include: an individual with a lost arm who utilized a mechno-arm, beings with pulmonodes or artificial lungs to replace their damaged or diseased lungs, or someone who lost an eye or became blind having cybernetic implants for vision.