Screaming was essentially about pitch, with probably an intent to scare, to raise an alarm, to alert, or to shout at the top of one's lungs.
In 2268, Captain James T. Kirk asked Odona about her homeworld, and she said she did not remember. She also said, "I was standing in a large auditorium crowded with people. Thousands pressed in against me. I could hardly breathe. I was fighting for oxygen, screaming to get out." (TOS: "The Mark of Gideon")