Many years into the future, Peter Parker is now an old man who has retired from being Spider-Man and now works in a flower shop. Mary Jane Watson has died from exposure to radioactivity, due to Peter's radioactive semen.

Supervillains are now a thing of the past, and so are the heroes, as New York now has a new merciless police force called "The Reign". Mayor Walters announces a new protection system WEBB, to prevent the city from attacks.^[1]

Spider-Man was later killed by Daemos of Inheritors, by crushing his head with Mary Jane's tombstone.^[2]

• Peter Parker / Spider-Man
• J. Jonah Jameson
• Mary Jane Watson-Parker
• May Reilly-Parker
• Ben Parker
• Venom (Eddie Brock)
• Electro (Max Dillon)
• Scorpion (Mac Gargan)
• Mysterio (Quentin Beck)
• Hydro-Man (Morris Bench)
• Kraven the Hunter (Sergei Kravinoff)
• Sandman (William Baker)
• Susie Baker
• Mayor Waters
• Doctor Octopus (Otto Octavius)
• Hypno-Hustler (Antoine Delsoin)
• Chris
• Blasko
• Karl
• Morty
• West