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Paul J. Hergenrother

From Wikipedia, the free encyclopedia

Paul J. Hergenrother is an American chemist and the Kenneth L. Rinehart Jr. Endowed Chair in Natural Products chemistry at the University of Illinois Urbana-Champaign.[1] His research focuses on the development of organic small molecules with novel biological properties such as enzyme inhibitors and activators, chemotherapeutics, and antibacterial agents. In 2008 Hergenrother was awarded the Eli Lilly Award in Biological Chemistry.

Education

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Hergenrother attended college at University of Notre Dame. In 1999, Hergenrother earned his PhD in chemistry from the University of Texas, where he worked in the lab of Professor Stephen F. Martin.

Career and research

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From 1999 to 2001, Hergenrother completed an American Cancer Society postdoctoral fellowship at Harvard University in the lab of Professor Stuart Schreiber.[2] In 2001, Hergenrother became a faculty member in the department of chemistry at the University of Illinois Urbana-Champaign.

Notable papers

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Web of Science lists 215 publications authored by Hergenrother in peer-reviewed scientific journals that have been cited over 8000 times.[3] His three most cited research articles have been cited >200 times each.[4][5]

Awards and honors[1]

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References

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  1. ^ a b "Paul J. Hergenrother | Chemistry at Illinois". chemistry.illinois.edu. Retrieved 2023-01-07.
  2. ^ Kuruvilla, Finny G.; Shamji, Alykhan F.; Sternson, Scott M.; Hergenrother, Paul J.; Schreiber, Stuart L. (2002). "Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays". Nature. 416 (6881): 653–657. Bibcode:2002Natur.416..653K. doi:10.1038/416653a. ISSN 1476-4687. PMID 11948353. S2CID 4424969.
  3. ^ "Web of Science". Retrieved 7 January 2023.
  4. ^ Richter, Michelle F.; Drown, Bryon S.; Riley, Andrew P.; Garcia, Alfredo; Shirai, Tomohiro; Svec, Riley L.; Hergenrother, Paul J. (2017-05-18). "Predictive compound accumulation rules yield a broad-spectrum antibiotic". Nature. 545 (7654): 299–304. Bibcode:2017Natur.545..299R. doi:10.1038/nature22308. ISSN 0028-0836. PMC 5737020. PMID 28489819.
  5. ^ Huigens III, Robert W.; Morrison, Karen C.; Hicklin, Robert W.; Flood Jr, Timothy A.; Richter, Michelle F.; Hergenrother, Paul J. (2013). "A ring-distortion strategy to construct stereochemically complex and structurally diverse compounds from natural products". Nature Chemistry. 5 (3): 195–202. Bibcode:2013NatCh...5..195H. doi:10.1038/nchem.1549. ISSN 1755-4330. PMC 3965367. PMID 23422561.
  6. ^ "Previous Eli Lilly Award in Biological Chemistry Recipients" (PDF). ACS Division of Biological Chemistry. Retrieved 7 January 2023.
  7. ^ "The David W. Robertson Award". www.acsmedchem.org. Retrieved 2023-01-07.