Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 2001 Aug;156(4):481-4.
doi: 10.1007/s002130100815.

The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects

C Stough  1 , J Lloyd, J Clarke, L A Downey, C W Hutchison, T Rodgers, P J Nathan
Affiliations
Clinical Trial

The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects

C Stough et al. Psychopharmacology (Berl). 2001 Aug.

Erratum in

  • Psychopharmacology (Berl). 2015 Jul;232(13):2427. Dosage error in article text

Abstract

Rationale: Extracts of Bacopa monniera have been reported to exert cognitive enhancing effects in animals. However, the effects on human cognition are inconclusive.

Objective: The current study examined the chronic effects of an extract of B. monniera (Keenmind) on cognitive function in healthy human subjects.

Methods: The study was a double-blind placebo-controlled independent-group design in which subjects were randomly allocated to one of two treatment conditions, B. monniera (300 mg) or placebo. Neuropsychological testing was conducted pre-(baseline) and at 5 and 12 weeks post drug administration.

Results: B. monniera significantly improved speed of visual information processing measured by the IT task, learning rate and memory consolidation measured by the AVLT (P<0.05), and state anxiety (P<0.001) compared to placebo, with maximal effects evident after 12 weeks.

Conclusions: These findings suggest that B. monniera may improve higher order cognitive processes that are critically dependent on the input of information from our environment such as learning and memory.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

Publication types

LinkOut - more resources