Generating samples under a Wright–Fisher neutral model of genetic variation

RR Hudson�- Bioinformatics, 2002 - academic.oup.com
RR Hudson
Bioinformatics, 2002academic.oup.com
A Monte Carlo computer program is available to generate samples drawn from a population
evolving according to a Wright–Fisher neutral model. The program assumes an infinite-sites
model of mutation, and allows recombination, gene conversion, symmetric migration among
subpopulations, and a variety of demographic histories. The samples produced can be used
to investigate the sampling properties of any sample statistic under these neutral models.
Availability: The source code for the program (in the language C) is available at http://home�…
Abstract
Summary: A Monte Carlo computer program is available to generate samples drawn from a population evolving according to a Wright–Fisher neutral model. The program assumes an infinite-sites model of mutation, and allows recombination, gene conversion, symmetric migration among subpopulations, and a variety of demographic histories. The samples produced can be used to investigate the sampling properties of any sample statistic under these neutral models.
Availability: The source code for the program (in the language C) is available at http://home.uchicago.edu/~rhudson1/source/mksamples.html.
Contact: rr-hudson@uchicago.edu
Oxford University Press