Featured Characters:

• Spider-Man (Peter Parker)
• Thing (Ben Grimm)
• Wolverine (Logan)
• Daredevil (Matt Murdock) (only on consoles and DS)
• Venom (Eddie Brock)
• Iron Man (Tony Stark)
• Captain America (Steve Rogers) (PSP exclusive)
• Magneto (Erik Lehnsherr)
• Elektra (Elektra Natchios)
• Storm (Ororo Munroe)
• Human Torch (Johnny Storm) (only on consoles and DS)
• Doctor Doom (Victor von Doom) (as PSP exclusive)

Supporting Characters:

• Imperfects
  • Paragon (Maya)
  • Johnny Ohm (John Ostrum)
  • Brigade (Rick Landau)
  • Solara (Reiko Kurokaki)
  • The Wink (Benedetta Gaetani)
  • Fault Zone (Maria Petrova)
  • Hazmat (Keith Kilham)

Antagonists:

• Niles Van Roekel

Other Characters:

• Punisher (Frank Castle) (First appearance) (Apparent death)
• Hulk (Bruce Banner) (First appearance) (Apparent death)
• Ben Parker (Mentioned) (Death)^[1]
• Burglar (Mentioned)^[2]
• New Avengers (Mentioned)^[3]
• Mister Fantastic (Reed Richards) (Mentioned)

Locations:

• Earth-50701
  • Earth
    • United States of America
      • New York
        • New York City
          • Manhattan
            • Midtown
              • Murray Hill
                • 39th Street and Second Avenue
                  • Daily Bugle Building

Items:

• Spider-Man's Suit
• Web-Shooters
• Wolverine's Suit
• Daredevil's Suit
• Daredevil's Billy Club
• Venom Symbiote
• Iron Man Armor
• Captain America's Uniform
• Captain America's Shield
• Magneto's Helmet
• Elektra's Twin Sai
• Doctor Doom's Armor
• Punisher's Suit
• Punisher's Arsenal

Vehicles:

Venom, Wolverine, Iron Man, Spider-Man and the rest of New York's heroes and villains are pitted against The Imperfects.

Actor	Voice role
Mark Acheson	Brigade (Rick Landau)
Alistair Abell	Spider-Man (Peter Parker)
Jason Bryden	Venom (Eddie Brock)
Larry Pierre Davids	Hazmat (Keith Kilham)
Michael Dobson	Johnny Ohm (John Ostrum) / Niles Van Roekel
Laura Garofano	The Wink (Benedetta Gaetani)
Christopher Gaze	Magneto (Max Eisenhardt)
Mark Gibbon	The Thing (Ben Grimm)
Mark Hildreth	Daredevil (Matt Murdock)
Jani Jakovac	Elektra (Elektra Natchios)
David Kaye	Iron Man (Tony Stark) / Wolverine (Logan)
Tina Krohn	Fault Zone (Maria Petrova)
Estelle Liebenberg	Storm (Ororo Munroe)
Camille Lopez	Paragon (Maya)
Kirby Morrow	Human Torch (Johnny Storm)
Ester Weisz	Solara (Reiko Kurokaki)

• Although the game was intended to be the start of a series, it failed critically and financially, canceling future sequels.
• It was the first game to be created by an EA and Marvel partnership. It started in 2005 and ended in 2007.
• The PSP port is drastically different in both gameplay and style, and even replaces two characters (Human Torch and Daredevil) with Doctor Doom and Captain America.
• There was a six issue comic book series based on the Imperfects, intended as a prequel and setup for unfolding events in the game.
• In Marvel vs. Capcom 3, there is a costume for Spider-Man that is neon green and dark black, nearly identical compared to the "evil" costume Spider-Man has in Marvel Nemesis.
• It's been rumored that EA, who published Marvel Nemesis, forced the developers to rush the game so they could make profit off of the series.
• No further material has been made for the characters featured in the game.