The association between periodontitis and other chronic diseases, such as cardiovascular disease (CVD) and type 2 diabetes mellitus, could be related to systemic inflammation initiated by a local inflammatory challenge. Oliveira et al. have added lack of oral hygiene, and its link with systemic inflammation, to the spectrum of risk factors for CVD.
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Genco, R., Van Dyke, T. Reducing the risk of CVD in patients with periodontitis. Nat Rev Cardiol 7, 479–480 (2010). https://doi.org/10.1038/nrcardio.2010.120
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DOI: https://doi.org/10.1038/nrcardio.2010.120