doi: 10.1093/bioinformatics/18.2.337.
Generating samples under a Wright-Fisher neutral model of genetic variation
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- PMID: 11847089
- DOI: 10.1093/bioinformatics/18.2.337
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Generating samples under a Wright-Fisher neutral model of genetic variation
Bioinformatics.
2002 Feb.
Abstract
A Monte Carlo computer program is available to generate samples drawn from a population evolving according to a Wright-Fisher neutral model. The program assumes an infinite-sites model of mutation, and allows recombination, gene conversion, symmetric migration among subpopulations, and a variety of demographic histories. The samples produced can be used to investigate the sampling properties of any sample statistic under these neutral models.
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